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'''Penn Medicine''' is the University of Pennsylvania's integrated academic medical center, comprising the Perelman School of Medicine, the Hospital of the University of Pennsylvania, and a network of hospitals, outpatient facilities, and physician practices throughout the Philadelphia region. As one of the nation's leading academic health systems, Penn Medicine combines patient care, medical education, and biomedical research, employing over 40,000 people and generating billions in annual revenue. The institution traces its origins to 1765, when the colonies' first medical school was established at Penn.<ref name="pennmed">{{cite web |url=https://www.pennmedicine.org/about |title=About Penn Medicine |publisher=University of Pennsylvania Health System |access-date=December 30, 2025}}</ref> == History == The University of Pennsylvania School of Medicine, founded in 1765, was the first medical school in the American colonies. Established by Drs. John Morgan and William Shippen Jr., the school trained physicians using European models emphasizing formal education rather than apprenticeship alone. This founding positioned Philadelphia as America's medical education center during the revolutionary and early national periods.<ref name="pennmed"/> The Hospital of the University of Pennsylvania (HUP) opened in 1874 on its current West Philadelphia campus, providing clinical facilities for medical education while serving the community. The hospital grew through the twentieth century, adding facilities, expanding services, and developing specialties that established its reputation among the nation's elite academic medical centers. Major buildings including the Silverstein Pavilion and the Perelman Center for Advanced Medicine expanded capacity and capabilities.<ref name="pennmed"/> Penn Medicine's current form emerged from the integration of clinical operations with the medical school, creating a unified academic health system. Acquisitions of community hospitals including Pennsylvania Hospital (ironically, the nation's oldest hospital, predating HUP), Chester County Hospital, and Lancaster General Health expanded the system's regional reach. This growth transformed Penn from a single academic medical center into a regional health system while maintaining academic and research missions.<ref name="pennmed"/> == Facilities == === Hospital of the University of Pennsylvania === The flagship hospital operates approximately 800 beds on the West Philadelphia campus, providing tertiary and quaternary care including transplant surgery, cancer treatment, cardiac care, and other advanced services. The hospital's trauma center serves as a regional resource for seriously injured patients, while specialized programs in numerous medical and surgical fields attract patients from throughout the region and beyond.<ref name="pennmed"/> === Penn Presbyterian Medical Center === Located in University City, Penn Presbyterian provides community and specialty services including a Level I trauma center, cardiac surgery, and neurosciences programs. The hospital serves the West Philadelphia community while complementing HUP's academic programs.<ref name="pennmed"/> === Pennsylvania Hospital === Founded in 1751 by Benjamin Franklin and Dr. Thomas Bond, Pennsylvania Hospital is America's first hospital. Now part of Penn Medicine, it operates approximately 500 beds in Washington Square West, providing community services and specialty programs including orthopedics and behavioral health. The historic institution maintains connections to its founding while functioning as part of the modern health system.<ref name="pennmed"/> == Research and Education == The Perelman School of Medicine conducts extensive biomedical research, receiving over one billion dollars annually in NIH funding—ranking it among the nation's top recipients. Research programs span basic science, translational research, and clinical trials across virtually every medical specialty. The gene therapy that cured some forms of inherited blindness, CAR-T cell therapy for cancer, and numerous other advances emerged from Penn research programs.<ref name="pennmed"/> Medical education encompasses MD training, graduate medical education (residencies and fellowships), and continuing education for practicing physicians. The medical school's highly selective admissions and comprehensive curriculum prepare physicians for careers in academic medicine, specialty practice, and primary care. Penn graduates lead medical institutions throughout the country.<ref name="pennmed"/> == Regional Presence == Penn Medicine has expanded throughout the Philadelphia region through acquisitions, partnerships, and new construction. The system now includes hospitals in Chester County, Lancaster, and southern New Jersey, along with numerous outpatient facilities providing primary and specialty care throughout the region. This expansion extends Penn's reach while generating revenue that supports academic and research missions.<ref name="pennmed"/> The health system employs physicians in practices throughout the region, integrating primary care, specialty services, and hospital care. This employed physician model, common among academic health systems, enables coordination while raising questions about market concentration and pricing that have drawn regulatory attention to hospital systems nationally.<ref name="pennmed"/> == See Also == * [[Perelman School of Medicine]] * [[Hospital of the University of Pennsylvania]] * [[Pennsylvania Hospital]] * [[University of Pennsylvania]] * [[Philadelphia Healthcare]] == References == <references /> {{#seo: |title=Penn Medicine - University of Pennsylvania Health System |description=Penn Medicine is the University of Pennsylvania's academic medical center, comprising the nation's first medical school, HUP, and a regional network of hospitals and practices. |keywords=Penn Medicine, University of Pennsylvania, Hospital of the University of Pennsylvania, Perelman School of Medicine, academic medical center, Philadelphia hospitals, Pennsylvania Hospital |type=Article }} [[Category:Healthcare]] [[Category:Hospitals]] [[Category:Universities]] [[Category:West Philadelphia]] [[Category:Medical Education]]
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